Identification of Phosphorylation Sites

FERRARESE A, MARIN O, BUSTOS VH, VENERANDO A, ANTONELLI M, ALLENDE JE, PINNA LA. Chemical dissection of the APC Repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3.
Biochemistry ,46(42), 11902-10 (2007).

BUSTOS V., FERRARESE A, VENERANDO A, MARIN O, ALLENDE JE, PINNA LA. The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1.
Proc Natl Acad Sci U S A 103(52), 19725-30 (2006).

  Antibodies to Peptides and Phosphopeptides

F. FILIPPINI, V. ROSSI, O. MARIN, M. TROVATO, P. COSTANTINO, P. MARK DOWNEY, F. LO SCHIAVO, M. TERZI: A plant oncogene as a phosphatase.Nature 379, 499-500, (1996).

GIOVANNI DI MAIRA, MAURO SALVI, GIORGIO ARRIGONI, ORIANO MARIN, STEFANIA SARNO, FRANCESCA BRUSTOLON, LORENZO A. PINNA AND MARIA RUZZENE
Protein kinase CK2 phosphorylates and upregulates Akt/PKB
CELL DEATH DIFFER 12 (6), 668-677 (2005).

COCCETTI P, TRIPODI F, TEDESCHI G, NONNIS S, MARIN O, FANTINATO S, CIRULLI C, VANONI M, ALBERGHINA L. The CK2 phosphorylation of catalytic domain of Cdc34 modulates its activity at the G1 to S transition in Saccharomyces cerevisiae.
Cell Cycle 2008, 7(10),1391-401.

  Cellular Uptake of Peptides

TONELLO F., SEVESO M., MARIN O., MOCK M., MONTECUCCO C.: Screening inhibitors of anthrax lethal factor
Nature 2002, 418, 386.

REALDON S, GEROTTO M, DAL PERO F, MARIN O, GRANATO A, BASSO G, MURACA M, ALBERTI A.
Proapoptotic effect of hepatitis C virus CORE protein in transiently transfected cells is enhanced by nuclear localization and is dependent on PKR activation.
J HEPATOL 40 (1): 77-85 (2004).

  Specific Peptide Substrates

MARIN O., MEGGIO F. AND PINNA L.A.:
Design and synthesis of two new peptide substrates for the specific and sensitive monitoring of casein kinases-1 and -2.
Biochem. Biophys. Res. Commun., 198, 3, 898-905, (1994)

M. LASA-BENITO, O. MARIN, F. MEGGIO, L.A. PINNA:
Golgi apparatus mammary gland casein kinase: monitoring by a specific peptide substrate and definition of specificity determinants.
FEBS Lett. 382, 149-152 (1996).

MARIN O , BRUNATI A.M.,BISINELLA A., SALVIATI A. and PINNA L.A.:
Novel consensus sequenze for the Golgi apparatus casein kinase, revealed using proline-rich protein-1 (PRP1)-derived peptide substrates.
BIOCHEM. J., 351, 765-768 (2000).

ARIANNA DONELLA-DEANA, ORIANO MARIN§, LUCA CESARO, ROSALIND H. GUNBY, ANNA FERRARESE, CARMEN TARTARI, LUCA MOLOGNI, LEONARDO SCAPOZZA, CARLO GAMBACORTI-PASSERINI AND LORENZO A. PINNA.
Unique substrate specificity of anaplastic lymphoma kinase (ALK): Development of phosphoacceptor peptides for the assay of ALK activity
BIOCHEMISTRY-US 44 (23), 8533-8542(2005).

FERRARI S, MARIN O, PAGANO MA, MEGGIO F, HESS D, EL-SHEMERLY M, KRYSTYNIAK A, PINNA LA Aurora-A site specificity: a study with synthetic peptide substrates
BIOCHEM J 390, 293-302 (2005).

SALVI M, SARNO S, MARIN O, MEGGIO F, ITARTE E, PINNA LA
Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits
FEBS LETT 580 (16), 3948-3952 (2006).

  Structural Studies

SETTIMO L, DONNINI S, JUFFER AH, WOODY RW, MARIN O.<br />
Conformational changes upon calcium binding and phosphorylation in a synthetic fragment of calmodulin.<br />
Biopolymers 88(3), 373-85 (2007).

  Chemical Synthesis of Protein

FRARE E, DE LAURETO P., SCARAMELLA E, TONELLO F, MARIN O, DEANA R, FONTANA A<br />
Chemical synthesis of the RGD-protein decorsin: Pro -> Ala replacement reduces protein thermostability<br />
PROTEIN ENG 10, 487-495 (2005).