1989 - High School Diploma Liceo Scientifico “A. Pacinotti”, La Spezia (60/60)

1994 - Degree in Biological Sciences, University of Pisa (110/110 cum laude)

1994 - Diploma in Biological Sciences, Scuola Normale Superiore, Pisa

1998 - PhD in Neurobiology, Scuola Normale Superiore, Pisa (70/70 cum laude)

1998-1999 - Research Fellow, Fondazione Levi-Montalcini, Rome

1999-2001 - Post-doctoral fellow, Scuola Normale Superiore, Pisa

2001-2007 – Researcher, CNR Neuroscience Institute, Pisa

2007-2010 – Senior Researcher, CNR Neuroscience Institute, Pisa

2010-2018 – Director of Research, CNR Neuroscience Institute, Pisa

2013-2018 – Head, Florence and Pisa Units, CNR Neuroscience Institute, Pisa

2018 – Associate Researcher, CNR Neuroscience Institute, Pisa

2018 – Professor of Physiology, Dept Biomedical Sciences, University of Padua

[Full CV with publications]

Matteo Caleo began his studies with Lamberto Maffei, one of the fathers of Italian neurophysiology. During his PhD and Post-doc at the Scuola Normale Superiore, he worked mainly on the role of neurotrophic factors in the degeneration and plasticity of the visual system. After becoming Group Leader at the CNR Neuroscience Institute in Pisa, he focused on the role of inter-hemispheric, transcallosal connections in the development and plasticity of the visual cortex. He also started a line of research in collaboration with Cesare Montecucco and Gipi Schiavo, devoted to the central effects of botulinum neurotoxins (BoNTs). In particular, he demonstrated that BoNT/A (widely used in clinical neurology for treatment of dystonia and spasticity) is retrogradely transported to the central nervous system following peripheral administration. More recently, his group has focused on the study of neuronal plasticity in different pathological conditions (stroke, brain tumors, epilepsy). The laboratory is located at the CNR Neuroscience Institute and is also being settled at the Dept of Biomedical Sciences in Padua.

Spalletti C, Alia C, Lai S, Panarese A, Conti S, Micera S, Caleo M (2017) Combining robotic training and inactivation of the healthy hemisphere restores pre-stroke motor patterns in mice. eLife 6: e28662.

Vannini E, Olimpico F, Middei S, Ammassari-Teule M, de Graaf EL, McDonnell L, Schmidt G, Fabbri A, Fiorentini C, Baroncelli L, Costa M, Caleo M (2016) Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function. Neuro-Oncology 18: 1634-1643.

Deidda G, Allegra M, Cerri C, Naskar S, Bony G, Zunino G, Bozzi Y, Caleo M*, Cancedda L* (2015) Early depolarizing GABA controls critical period plasticity in the rat visual cortex. Nat Neurosci 18(1): 87-96.

Restani L, Cerri C, Pietrasanta M, Gianfranceschi L, Maffei L, Caleo M (2009) Functional masking of deprived eye responses by callosal input during ocular dominance plasticity. Neuron 64(5): 707-718.

Antonucci F, Rossi C, Gianfranceschi L, Rossetto O, Caleo M (2008) Long-distance retrograde effects of botulinum neurotoxin A. J Neurosci 28:3689-3696.

AIRC (Italian Association on Cancer Research)

European Union (H2020)

CNR – Joint Laboratories

Ministry of Education and Research (PRIN project)