I graduated in Biological Science in 1991 at University of Padua and then I had my PhD in Enviromental Medicine in 1997. After 1997 I worked as biologist in the Operating Unit of Trasfusional and Immunoematology Service - of Treviso Hospital with a contract of collaboration.

From 2001 I have worked in muscle physiology, first as post-doc and then as established researcher, studying several aspects of skeletal muscle. In particular I’ve studied some aspects of muscle plasticity as

 

  • expression of sarcomeric isoforms of myosin as a key protein for mechanical performance of skeletal fibres and their functional properties in mammals and human
  • physiological responses of muscle to various stimuli such as training, immobilization, denervation, or the physiological conditions such as aging. During aging the muscle undergoes a progressive weakening and mass reduction: this condition, named sarcopenia, is the result of many causes. Physical activity can contribute to counteract sarcopenia. The comparison of adaptations to activity of muscle fiber in young and elderly can help us to understand the pathway that brings at this muscle condition.

Specific expertise: chemical analytical techniques, electron microscopy, culture of primary and immortalized cells , mono and bi-dimensional electrophoresis and immunoblotting, muscle biophysics of whole muscles and single muscle fibers.

Authors of 34 papers indexed in Pubmed with 533 citations and h index 13

Doria C, Toniolo L, Verratti V, Cancellara P, Pietrangelo T, Marconi V, Paoli A, Pogliaghi S, Fano G, Reggiani C, Capelli C. Improved V'O2 uptake kinetics and shift in muscle fiber type in high altitude trekkers. J Appl Physiol. 2011 Aug 25.

Toniolo L, Cancellara P, Maccatrozzo L, Patruno M, Mascarello F, Reggiani C. Masticatory myosin unveiled: first determination of contractile parameters of muscle fibers from carnivore jaw muscles. Am J Physiol Cell Physiol. 2008 Dec;295(6):C1535-42.

Toniolo L, Maccatrozzo L, Patruno M, Pavan E, Caliaro F, Rossi R, Rinaldi C, Canepari M, Reggiani C, Mascarello F. Fiber types in canine muscles: myosin isoform expression and functional characterization. Am J Physiol Cell Physiol. 2007 May;292

Toniolo L, Maccatrozzo L, Patruno M, Caliaro F, Mascarello F, Reggiani C. Expression of eight distinct MHC isoforms in bovine striated muscles: evidence for MHC-2B presence only in extraocular muscles. J Exp Biol. 2005 Nov;208(Pt22):4243-53.

Toniolo L, Patruno M, Maccatrozzo L, Pellegrino MA, Canepari M, Rossi R, D'Antona G, Bottinelli R, Reggiani C, Mascarello F. Fast fibres in a large animal: fibre types, contractile properties and myosin expression in pig skeletal muscles. J Exp Biol. 2004 May;207(Pt 11):1875-86.

  • Ex 60%;
  • PRIN 2010/2011 Impact of Physical Activity on healthy aging: multidisciplinary analysis of mechanisms and outcomes;
  • Pangea;
  • Myoscreen;