Present position: Lecturer of General Pathology , University of Padova. Visiting scientist, Max-Planck-Institute of Biochemistry, Germany.
Educational qualification: Ph.D. in Cell Biology and Pathology, University of Padova, Italy.

Present work experience
April 2012- March 2014: Post-doctoral fellow at Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, in the group coordinated by Prof Matthias Mann.
Research interests: Mass spectrometry-based proteomics applied to skeletal muscle.
1999 to present: Lecturer, Applied Biology and General Pathology (University of Padova).
Research interests: Activity-dependent gene regulation in skeletal muscle.

Post-doctoral experience

2001-2003: Postdoctoral fellow in the laboratory of Prof. Axel Ullrich, Max-Planck-Institute for Biochemistry, Martinsried, Germany.
Recipient of an EMBO long-term fellowship, 2000-2001
Recipient of a Marie Curie Individual Fellowship MCFI-2000-01360. 2001-2003, Life Sciences.

Graduate studies
PhD in Cell Biology and Pathology in the laboratory of Prof. T. Pozzan at the Department of Biomedical Sciences, Padova.
Research interests: signal transduction and calcium signalling, single cell calcium imaging.

I use mass spectrometry (MS)-based proteomics as a tool to investigate structure-function relationships in skeletal muscle. My present interest focus both on the proteome of individual muscle fibers and on a comprehensive skeletal muscle proteome to be used as a resource in the field. I also apply MS-based proteomics to the study of alternative splicing and exon skipping of sarcomeric proteins. The possibility of interacting and collaborating with the Department of Proteomics and Signal Transduction at Max-Plack-Institute of Biochemistry offers the invaluable opportunity to be exposed to the major advances in all aspects of the field, ranging fro sample preparation, to novel instruments and to computational proteomics. I plan to apply the knowledge I could acquire so far to the context of genetic and acquired striated muscle diseases.

 

  1. Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging Murgia M, Toniolo L, Nagaraj N, Ciciliot S, Vindigni V, Schiaffino S, Reggiani C, Mann M. Cell Rep. 2017 Jun 13;19(11):2396-2409.
  2. Mitochondrial specialization revealed by single muscle fiber proteomics: focus on the Krebs cycle Schiaffino S, Reggiani C, Kostrominova TY, Mann M, Murgia M. Scand J Med Sci Sports. 2015 Dec;25 Suppl 4:41-8.
  3. Molecular diversity and pleiotropic role of the mitochondrial calcium uniporter M Murgia, R Rizzuto 2015 Cell Calcium 58 (1), 11-17
  4. Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways, and transcription factors Deshmukh AS, Murgia M, Nagaraj N, Treebak JT, Cox J, Mann M. Mol Cell Proteomics. 2015 Apr;14(4):841-53
  5. Single muscle fiber proteomics reveals unexpected mitochondrial specialization Murgia M, Nagaraj N, Deshmukh AS, Zeiler M, Cancellara P, Moretti I, Reggiani C, Schiaffino S, Mann M. EMBO Rep. 2015 Mar;16(3):387-95.